Supply-Side Optimization with AI: The Future of Programmatic Advertising

Britany Scott

February 25, 2025

20

minutes read

As digital advertising progresses toward a projected $779 billion in global programmatic spend by 2026, the industry faces a sobering reality: approximately 40% of advertising budgets are currently lost to supply chain inefficiencies, from opaque intermediaries to fraudulent traffic.

The proliferation of selling channels, bid duplication, and complex auction mechanics has created an opaque ecosystem where advertising dollars navigate a labyrinthine path before reaching publishers.

The traditional approach of manual supply path buying, while valuable, has proven insufficient to address the scale and dynamism of modern programmatic trading. As bid streams grow exponentially and new channels emerge, human operators can no longer effectively optimize across thousands of supply permutations in real time. This has driven the industry toward AI-powered supply path optimization (SPO) solutions that can process vast amounts of bid data, identify inefficient paths, and automatically redirect spend toward optimal routes.

For brands and agencies, mastering AI-driven supply-side efficiency is no longer optional - it’s essential. The pressure to maximize every advertising dollar is intensifying, with most executives prioritizing budget efficiency and 55% increasing AI investments. In an industry where 84% of digital ad spend will be programmatic by 2026, those who fail to adopt AI-driven solutions risk falling behind. But for those who embrace AI, the opportunity extends beyond cost-cutting - it’s about unlocking new levels of agility, precision, and privacy-compliant targeting.

To understand how brands can turn supply-side inefficiencies into competitive advantages, we’ll explore:

  • The Problem, by dissecting the inefficiencies plaguing traditional supply paths, and
  • The Solution with a detailed look at how AI-powered supply-side optimization is transforming the industry.

The Problem: Inefficiencies in Traditional Supply Paths

Despite the rapid growth of programmatic advertising, inefficiencies within the supply chain continue to drain budgets and hinder performance. From non-transparent auction dynamics and hidden fees to redundant supply paths and Demand-Side Platform (DSP) biases, these inefficiencies inflate costs and limit advertisers’ ability to reach high-quality audiences. 

Let’s explore each of these components of the bigger problem in greater detail below:

Lack of transparency fuels auction inefficiencies

The programmatic ecosystem, while designed for efficiency, often suffers from a lack of transparency that drives up costs and reduces effectiveness.

  • Bid duplication: Publishers often syndicate their inventory across multiple Supply-Side Platforms (SSPs), leading to bid duplication and artificial competition. While the exact number of SSPs varies, research suggests an average publisher works with 10+ SSPs. This practice inflates CPMs and diminishes win rates, forcing advertisers to pay more for the same impressions. 

For example, an advertiser bidding $5 CPM may find that, due to redundant auctions, they are effectively bidding against themselves across multiple SSPs - driving up costs without increasing actual media value.

  • Auction bias: Incentives and rebates within the supply chain can skew auction dynamics. DSPs may prioritize SSPs offering higher margins or kickbacks, even if those paths aren't the most cost-effective for the advertiser. This lack of transparency makes it difficult for advertisers to understand the true cost of their impressions and ensure they're getting the best value.

Consider an example. An advertiser sets a $7 CPM bid for a premium inventory spot on an open exchange. However, their DSP - due to a preferential agreement with a specific SSP - routes their bid through a higher-cost supply path, where the same inventory is being resold at $9 CPM instead of the original $7. The advertiser unknowingly overpays 28% more for the same impression, while the DSP and SSP pocket the difference through undisclosed fees. As a result, rather than securing the best price for the advertiser, the DSP maximizes its own revenue, ultimately reducing media efficiency and ROI.

Hidden fees and supply chain redundancy erode value

The complexity of the programmatic supply chain creates opportunities for hidden fees and redundancies that drain ad budgets.

  • The "tech tax": Each intermediary in the programmatic chain - SSPs, resellers, data providers, and verification vendors - takes a cut of the ad spend. As a result, 40% of budgets disappear into undisclosed fees, with a single impression often passing through 4–10 vendors, adding $0.15–$0.30 in hidden costs per impression.

For instance, an ad campaign with a $10 million budget may see only $4.7 million reach actual media placements, while the rest is consumed by intermediary fees, invalid traffic, and non-viewable impressions.

  • Made-for-Advertising (MFA) waste: Despite industry efforts to improve inventory quality, 6.2% of programmatic budgets still flow to low-quality MFA sites. These sites, optimized for ad revenue over user value, deliver 63% higher cost-per-conversion compared to premium inventory. The ANA’s 2024 audit revealed that only 43.9% of DSP spend directly reaches consumers. MFA domains, often cloaked as legitimate publishers, leverage high-volume clickbait and bot traffic to siphon budgets. For a Fortune 500 brand, this translated to $10 million wasted on MFA sites in 2023.

For instance, a retail brand launches a $500,000 programmatic campaign, expecting to reach high-intent shoppers on premium publisher sites. However, due to lax inventory filtering, a portion of their budget is allocated to an MFA site - a low-quality blog overloaded with ads and no real audience engagement. While the campaign reports a high number of impressions, site analytics reveal that 80% of visits lasted under one second, and click-through rates were near zero. The brand unknowingly wasted over $30,000 on ad placements that never reached real consumers, undermining performance goals and skewing campaign metrics.

DSP biases and walled gardens exacerbate the problem

DSPs and walled gardens introduce additional layers of complexity and cost to the programmatic supply chain.

  • Algorithmic favoritism: DSPs often prioritize exchanges with favorable revenue-sharing agreements, maximizing their own profits rather than ensuring optimal advertiser ROI. This results in higher CPMs and reduced efficiency, forcing advertisers to spend more for the same impressions. This collusion risk is now under legal scrutiny: the DOJ’s 2024 Gibson v. Cendyn filing argued that algorithm providers facilitating price alignment could constitute Sherman Act violations.
  • Walled Garden monopolies: Google, Meta, and Amazon now control 61% of digital ad spend, limiting cross-platform measurement and data portability. Their closed ecosystems inflate CPMs by 20–30% compared to open-web alternatives, restricting advertisers from gaining a holistic view of their campaign performance.

For example, advertisers running cross-channel campaigns struggle to measure reach and frequency across platforms, leading to ad fatigue, overspending, and loss of potential reach. This lack of transparency forces brands to trust self-reported metrics, which can often be biased or misleading.

The real-world impact on CPM and ad performance

The cumulative effect of these inefficiencies is significant:

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Why is a focus on supply-side optimization critical in 2025 & why must advertisers act now?

With third-party cookies disappearing and privacy regulations tightening, the inefficiencies of traditional supply paths will only become more apparent. Advertisers who fail to optimize their supply chains risk campaigns in low-quality inventory, and ineffective ad placements.

In the next section, we’ll explore how AI-powered supply path optimization (SPO) is transforming programmatic efficiency - reducing waste, increasing transparency, and ensuring that every ad dollar is spent strategically.

The Solution: AI-Powered Supply-Side Optimization

As programmatic advertising evolves, artificial intelligence has emerged as the key to untangling supply chain complexity and eliminating inefficiencies. AI-driven supply path optimization (SPO) represents a fundamental shift from reactive to proactive supply chain management, using machine learning to identify and prioritize the most effective paths to premium inventory while eliminating unnecessary costs. 

Below, we’ll examine how AI-powered SPO stacks up against traditional curation models and how AI Digital sets a new benchmark for supply optimization.

What is supply-side optimization?

Supply-side optimization (SPO) is the process of strategically managing and refining the channels through which advertisers purchase ad inventory. It involves analyzing various factors, such as supply partners, ad exchanges, and bidding strategies, to ensure that ad impressions are purchased efficiently and effectively. The goal of SPO is to maximize return on investment (ROI) by minimizing wasted ad spend and improving key performance indicators (KPIs) like viewability, click-through rates, and conversions. Traditional SPO often relies on manual analysis and adjustments, which can be time-consuming and less effective in a programmatic landscape.

AI vs. traditional curation: The competitive edge

As mentioned, traditional approaches to supply path optimization, while foundational to the industry's development, are increasingly unable to keep pace with the complexity and scale of modern digital advertising. 

What inefficiencies exist in traditional supply paths?: Limitations of traditional curation

Traditional supply-side curation, built around human-managed Private Marketplace (PMP) deals, faces several critical challenges:

  • Static deal structure: Manual PMP deals are typically set up with fixed parameters and require human intervention to adjust. This rigid structure means they can't adapt quickly to changing market conditions or performance fluctuations.
  • Generic optimization: Traditional curation often relies on broad contextual relevance and basic data partnerships, leading to generalized targeting that doesn't account for specific advertiser objectives. These approaches focus on industry-standard metrics rather than client-specific KPIs.
  • Resource-intensive management: Human operators must manually review performance data, adjust targeting parameters, and optimize bid strategies - a time-consuming process that can't scale effectively across thousands of campaigns.
  • Delayed response times: With human-managed systems, optimization cycles are typically days or weeks long, meaning opportunities for improvement are often identified long after they could have made an impact.

How does AI improve supply-side optimization compared to manual curation?

To overcome these limitations, AI-driven curation introduces a dynamic, scalable, and highly efficient alternative. Unlike traditional methods, AI-powered solutions leverage real-time data processing, machine learning algorithms, and automated decision-making to optimize supply paths in a way that is both adaptive and performance-driven. AI continuously monitors market conditions, audience behaviors, and inventory performance, allowing for instant adjustments that ensure advertisers access the highest-quality inventory at the most cost-effective rates. Additionally, AI's ability to process vast amounts of data instantaneously means that optimization cycles occur in real time, eliminating delays and unlocking continuous performance improvements.

One such AI-powered solution is AI Digital’s Smart Supply.

What is AI Digital's Smart Supply, and how does it enhance programmatic efficiency?

AI Digital’s Smart Supply is an AI-powered supply-side optimization and activation solution designed to enhance efficiency, transparency, and performance in programmatic advertising. It leverages machine learning and real-time data analysis to ensure advertisers access high-quality, fraud-free, and cost-effective inventory while eliminating inefficiencies in the supply chain.

So, how does Smart Supply deliver these benefits?  

Smart Supply enhances programmatic effectiveness through dynamic deal optimization, offering two sophisticated approaches to inventory optimization:

1. Deal Libraries: AI-optimized general inventory pools

  • AI Digital’s Deal Libraries consist of high-quality inventory pools, continuously optimized using real-time AI-driven analysis.
  • These daily-updated pools are ideal for broad-reach campaigns, such as video buys focused on completed views or high-impact brand awareness initiatives.
  • AI continuously refines the inventory selection, removing underperforming placements and prioritizing premium, high-engagement ad spaces.

2. Campaign-specific deals: Precision targeting for aggressive KPIs

  • Unlike static PMP deals, Smart Supply’s AI custom-builds campaign-specific deals tailored to advertiser-defined objectives.
  • These deals leverage real-time audience data and advanced contextual targeting to align with specific audience segments and aggressive KPIs.
  • AI dynamically monitors and adjusts bidding strategies to ensure optimal performance and cost efficiency throughout the campaign lifecycle.

By constantly adapting to live campaign data, Smart Supply’s AI-driven deal structures provide advertisers with unmatched flexibility, efficiency, and ROI maximization. However, dynamic deal optimization is just one piece of the puzzle - Smart Supply goes even further to enhance programmatic efficiency through advanced KPI alignment and performance-driven optimization.

Smart Supply’s custom KPI alignment: AI-driven performance optimization

While addressing platform bias and cost efficiency creates the foundation for effective programmatic advertising, Smart Supply goes further by shifting focus from standard industry metrics to advertiser-specific KPIs. Traditional curation models often rely on basic measurements like impressions or CPMs, which fail to capture the full impact of a campaign. Smart Supply's AI analyzes historical performance data to determine which inventory sources, placements, and bidding strategies are most effective for each unique advertiser.

The platform's real-time machine learning models continuously optimize supply paths based on live performance feedback, maximizing viewability, engagement, and conversions. Advertisers maintain full control and transparency through customized reporting dashboards that provide detailed insights into campaign efficiency improvements.

This comprehensive approach - combining bias elimination, cost efficiency, and custom KPI optimization - delivers not just incremental improvements but a fundamental transformation in how programmatic advertising operates. 

But while aligning with advertiser-specific KPIs and leveraging dynamic deal optimization are essential for performance, their true value is only realized when paired with rigorous quality control. Without ensuring premium, fraud-free inventory, even the most optimized campaigns can suffer from wasted spend and poor engagement.

Automated quality control: Ensuring premium, fraud-free inventory

Maintaining high-quality, brand-safe inventory is critical to programmatic success. Smart Supply leverages AI-powered filtering systems to:

  • Remove low-performing publishers: AI analyzes past performance data to eliminate low-engagement sites, ensuring only high-value inventory is included.
  • Eliminate indirect traffic: Smart Supply filters out unnecessary bid hops, preventing redundant intermediaries from inflating costs.
  • Implement invalid traffic (IVT) protection: AI applies advanced fraud detection models to block bot traffic and fraudulent inventory before ads are served.

Ensure brand safety via contextual crawling: Proprietary AI-driven contextual analysis verifies that ads appear in brand-safe, relevant environments.

With these safeguards in place, Smart Supply guarantees that advertisers invest only in clean, high-impact impressions, eliminating waste and maximizing ROI.

However, the real power of Smart Supply lies in its advanced bidding model, which intelligently optimizes every auction in real time. In the next section, we'll explore how this AI-driven bidding approach further enhances efficiency and performance.

Smart Supply’s real-time AI bidding model

As mentioned, one of Smart Supply’s most powerful innovations is its real-time AI bidding model, which ensures premium ad placements at the most efficient cost. Here’s how it works:

1. Intelligent path selection: Eliminating unnecessary costs

  • AI continuously evaluates all available inventory paths, selecting the most efficient and cost-effective routes to premium placements.
  • AI prevents bid stream recycling, where a $25 CPM bid inflates to $34+ due to multiple resellers and bid hops.

2. Precision targeting: Delivering ads to the right audience

  • AI enhances targeting through custom geotargeting and audience refinement, ensuring ads reach high-value users.
  • Real-time performance monitoring allows AI to adjust bids dynamically, maximizing engagement.
  • Direct supply path optimization ensures ads are served in the best placements without unnecessary cost inflation.
  • Brand safety verification guarantees that placements align with brand reputation guidelines.

3. Scale and efficiency: Optimizing performance across all channels

  • Smart Supply operates across Display, Streaming Video, Connected TV (CTV), and Streaming Audio, optimizing inventory selection for each format.
  • AI maintains consistent performance optimization across all channels, ensuring efficient ad spend allocation.

By leveraging real-time AI bidding, Smart Supply cuts costs, enhances targeting accuracy, and ensures premium ad placements at the best possible price.

👉 So, how does Smart Supply differentiate itself from other AI supply platforms? In essence, Smart Supply stands out through its DSP-agnostic approach, allowing advertisers to access premium inventory across multiple platforms without being confined to a single vendor's ecosystem. Unlike traditional curation platforms that often prioritize their owned-and-operated inventory, Smart Supply uses AI-driven evaluation metrics that assess inventory purely on performance merit. The platform's real-time machine learning models continuously optimize supply paths based on actual campaign outcomes rather than platform preferences, while operating on a transparent revenue-share model that eliminates hidden fees and unnecessary technical costs. 

Why Smart Supply is the present solution & future of AI-powered SPO

Traditional inventory curation approaches, with their manual processes and static optimization methods, simply cannot match the sophistication and efficiency of AI-powered solutions. Smart Supply's comprehensive approach addresses the fundamental challenges of programmatic advertising through automated intelligence and real-time optimization.

By combining advanced AI algorithms with deep industry expertise, Smart Supply delivers what traditional curation cannot: truly dynamic optimization, complete transparency, and measurable efficiency gains. The platform's ability to eliminate supply chain inefficiencies while maximizing performance makes it not just an enhancement to existing processes, but a fundamental transformation in how programmatic advertising operates.

The Power of Open Garden: Breaking Down Walled Gardens for True Optimization

Traditional SPO primarily focuses on eliminating inefficiencies in the programmatic supply chain. While AI-powered SPO takes this a step further by leveraging machine learning to optimize supply paths dynamically, the real impact comes when advertisers gain access to a truly open and transparent marketplace - one that isn’t restricted by DSP biases or walled garden limitations.

This is where AI Digital’s Open Garden approach comes into play. It extends the benefits of AI-powered SPO by ensuring:

  • Unbiased inventory access: Advertisers can select and optimize supply based purely on performance, without being pushed toward a specific platform’s owned-and-operated inventory.
  • Cross-platform data insights: Unlike walled gardens that silo data, Open Garden unifies insights across multiple DSPs, providing a holistic view of campaign performance.
  • AI-driven optimization without black boxes: Open Garden ensures advertisers see and control how AI optimizes supply paths, eliminating the opacity that often plagues traditional DSPs.

What makes AI Digital’s Open Garden approach unique?

AI Digital’s Open Garden is designed to dismantle walled garden restrictions and create a neutral, transparent advertising ecosystem. Here’s how it transforms AI-powered supply path optimization:

1. Neutral, DSP-agnostic execution

One of the biggest flaws in the current programmatic landscape is the bias in DSPs toward their own inventory. For example, Google’s DV360 prioritizes YouTube, while The Trade Desk promotes its highest-value partnerships. This self-serving model forces advertisers into inefficient supply paths and artificially inflates costs.

Open Garden removes these biases by enabling advertisers to buy across 15+ DSPs, ensuring that media spend is allocated based on performance rather than platform interests. This DSP-agnostic execution allows for:

  • Greater flexibility in choosing inventory sources
  • More competitive pricing due to increased supply diversity
  • Higher performance transparency without preferential treatment of specific exchanges

2. AI-powered transparency and optimization

Most DSPs operate as closed ecosystems, making it difficult for advertisers to understand why certain inventory is prioritized or how supply paths are optimized. Open Garden solves this by offering:

  • AI-driven supply path filtering, ensuring only premium, high-value inventory is selected
  • Transparent reporting on bid paths and media costs, eliminating hidden fees
  • Custom AI optimizations based on advertiser KPIs, rather than generic DSP metrics

This level of transparency allows advertisers to actively control their supply strategy while still benefiting from AI-powered automation.

3. Cross-platform data unification for smarter decision-making

Walled gardens keep valuable audience and performance data locked within their ecosystems, preventing advertisers from gaining a comprehensive view of their campaigns across different platforms. Open Garden counters this by:

  • Aggregating data across multiple DSPs and SSPs for a unified performance dashboard
  • Providing AI-driven insights that allow for more precise audience targeting and budget allocation
  • Enabling full-funnel attribution tracking, ensuring advertisers can measure the true impact of their media investments

The business impact of Open Garden-enabled AI SPO

By combining AI-powered supply path optimization with Open Garden’s unbiased execution, AI Digital delivers a powerful competitive advantage to advertisers. The key benefits include:

✅ +25% improvement in eCPM efficiency: Lower costs per impression through streamlined supply paths
✅ +11% increase in audience reach: Expanded access to premium inventory without walled garden constraints
✅ +16% reduction in Cost Per Acquisition: Better alignment between supply selection and campaign KPIs
✅ +23% Improvement in overall media efficiency: Reduced waste and optimized media spend allocation

Conclusion: Why AI-Powered Supply Optimization is Essential for 2025

As the digital advertising landscape becomes increasingly complex, the need for intelligent, unbiased supply path optimization has never been more critical. The traditional approaches of manual curation and platform-specific optimization are no longer sufficient to navigate a fragmented ecosystem of walled gardens, multiple demand sources, and evolving privacy regulations.

AI-powered supply optimization, particularly when combined with an open, transparent framework like AI Digital's Open Garden, represents more than just an improvement in programmatic efficiency - it's a fundamental transformation in how digital advertising operates. By leveraging artificial intelligence to evaluate supply paths, optimize bidding strategies, and ensure brand safety, advertisers can finally achieve the original promise of programmatic advertising: reaching the right audience with the right message at the right price, without waste or bias.

Moreover, as privacy regulations tighten and third-party cookies disappear, AI-driven optimization becomes even more crucial. Smart Supply's ability to maintain performance while adapting to these changes ensures that advertisers aren't just solving today's challenges but are prepared for tomorrow's evolution.

The question is no longer whether to adopt AI-powered supply optimization, but how quickly you can implement it to gain a competitive advantage. As the industry continues to evolve, those who embrace this technology will be better positioned to deliver superior campaign performance, maintain brand safety, and achieve greater return on their advertising investment.

To learn more about how Smart Supply can transform your programmatic advertising efficiency and effectiveness, visit AI Digital’s Smart Supply page. Discover how AI-powered optimization can help you navigate the complexities of the digital landscape while preparing for tomorrow's challenges.

Inefficiency

Description

CPM Inflamation

Indirect supply pathscost 2.8x more perimpression than direct routes. A $5 CPM on a direct path can balloon to $14when routed through multiple resellers, meaning the advertiser is paying almostthree times as much for the same potential exposure.

Ad performance decay

Longer, more complex supply paths introduce more points of failure. Technical glitches, latency issues, and slow loading times can all decrease the likelihood of an ad being fully rendered and viewed by the user.

Budget leakage

The ANA’s 2024 audit revealedthat only 43.9% of DSP spend directly reaches consumers, with the restlost to fees, non-viewable ads, and invalid traffic. This wasted ad spendreduces the value advertisers receive and negatively impacts campaigneffectiveness and ROI.

Use case

Description of use case

Examples of companies using AI

Ease of implementation

Impact

Audience segmentation and insights

Identify and categorize audience groups based on behaviors, preferences, and characteristics

  • Michaels Stores: Implemented a genAI platform that increased email personalization from 20% to 95%, leading to a 41% boost in SMS click through rates and a 25% increase in engagement.
  • Estée Lauder: Partnered with Google Cloud to leverage genAI technologies for real-time consumer feedback monitoring and analyzing consumer sentiment across various channels.
High
Medium

Automated ad campaigns

Automate ad creation, placement, and optimization across various platforms

  • Showmax: Partnered with AI firms toautomate ad creation and testing, reducing production time by 70% while streamlining their quality assurance process.
  • Headway: Employed AI tools for ad creation and optimization, boosting performance by 40% and reaching 3.3 billion impressions while incorporating AI-generated content in 20% of their paid campaigns.
High
High

Brand sentiment tracking

Monitor and analyze public opinion about a brand across multiple channels in real time

  • L’Oréal: Analyzed millions of online comments, images, and videos to identify potential product innovation opportunities, effectively tracking brand sentiment and consumer trends.
  • Kellogg Company: Used AI to scan trending recipes featuring cereal, leveraging this data to launch targeted social campaigns that capitalize on positive brand sentiment and culinary trends.
High
Low

Campaign strategy optimization

Analyze data to predict optimal campaign approaches, channels, and timing

  • DoorDash: Leveraged Google’s AI-powered Demand Gen tool, which boosted its conversion rate by 15 times and improved cost per action efficiency by 50% compared with previous campaigns.
  • Kitsch: Employed Meta’s Advantage+ shopping campaigns with AI-powered tools to optimize campaigns, identifying and delivering top-performing ads to high-value consumers.
High
High

Content strategy

Generate content ideas, predict performance, and optimize distribution strategies

  • JPMorgan Chase: Collaborated with Persado to develop LLMs for marketing copy, achieving up to 450% higher clickthrough rates compared with human-written ads in pilot tests.
  • Hotel Chocolat: Employed genAI for concept development and production of its Velvetiser TV ad, which earned the highest-ever System1 score for adomestic appliance commercial.
High
High

Personalization strategy development

Create tailored messaging and experiences for consumers at scale

  • Stitch Fix: Uses genAI to help stylists interpret customer feedback and provide product recommendations, effectively personalizing shopping experiences.
  • Instacart: Uses genAI to offer customers personalized recipes, mealplanning ideas, and shopping lists based on individual preferences and habits.
Medium
Medium